| 第 38 卷第 2 期 |  | Vol. 38 No. 2 | | 2008 年 4 月 | Apr 2008 |
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所屬欄目：醫藥及中間體
4-甲�；�(lián)苯的合成 |
| 李海峰，楊希志，王俊峰
（大慶油田化工有限公司 技術(shù)開(kāi)發(fā)研究院，黑龍江 大慶 163453） |
| 摘 要：以聯(lián)苯和一氧化碳為原料，Lewis 酸為催化劑羰基化合成4-甲�；�(lián)苯，利用紅外光譜、核磁共振及液相色譜等方法對產(chǎn)品進(jìn)行結構表征�？疾炝舜呋瘎┘胺磻獪囟鹊葪l件對4-甲�；�(lián)苯收率的影響。優(yōu)惠條件為：以三氯化鋁為主催化劑，氯化亞銅為助催化劑，反應溫度在45~50℃，反應時(shí)間24 h，n（聯(lián)苯） ∶ n（甲酰氯）=1 ∶ 1.5，m（三氯化鋁） ∶ m（聯(lián)苯）=1.3 ∶ 1，此條件下4-甲�；�(lián)苯的收率可達70%。 |
| 關(guān)鍵詞：4-甲�；�(lián)苯；聯(lián)苯；羰基化反應；催化劑 |
| 中圖分類(lèi)號：TQ241.5 文獻標識碼：A 文章編號：1009-9212（2008）02- 0038-02 |
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| Synthesis of 4-Biphenylbenzaldehyde |
| LI Hai-feng，YANG Xi-zhi， WANG Jun-feng
（Technology R&D Institution，Chemical Co. of Daqing Oilfield，Daqing 163453，China） |
| Abstract：Carbonization synthesis of 4-biphenylbenzaldehyde was made with biphenyl and carbon monoxide as raw material in the presence of Lewis acid catalyst. The structure of the product was characterized by infrared spectrum，nuclear magnetic resonance and liquid chromatography. The effects of catalyst and reaction temperature upon the yield of 4-biphenylbenzaldehyde were being investigated. The optimal conditions were as follow：aluminium trichloride as main catalyst，cuprous chloride as help catalyst reaction temperature 15~50℃，mass ratio of aluminium trichloride and biphenyl 1.3 ∶ 1. The yield of 4-biphenylbenzaldehyde could reach 70% under the optimal condition. |
| Key words：4-biphenylbenzaldehyde；biphenyl；carbonylation；catalyst |
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作者簡(jiǎn)介：李海峰（1974 -），男，廣東東莞人，工程師，碩士。（E-mail：richard00700@hotmail.com）
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收稿日期：2008-03-07
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