| 第 47 卷第 4 期 |  | Vol. 47 No. 4 | | 2017 年 8 月 | Aug 2017 |
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所屬欄目：香精香料
正交法優(yōu)化檸檬醛合成紫羅蘭酮工藝 |
| 楊海寬，溫世坊，李 江，章 挺，汪信東
（江西省林業(yè)科學(xué)院 國家林業(yè)局樟樹(shù)工程技術(shù)研究中心，江西 南昌 330032） |
| 摘 要：以檸檬醛和丙酮為原料，在氫氧化鈉催化條件下，經(jīng)羥醛縮合反應先制備假性紫羅蘭酮，再在磷酸催化條件下，經(jīng)環(huán)化反應制備紫羅蘭酮。采用正交法研究了一鍋法條件下，檸檬醛合成紫羅蘭酮工藝條件。合成假性紫羅蘭酮優(yōu)化工藝條件是：物料比n（檸檬醛） ∶ n（丙酮）=1 ∶ 6，催化劑用量比w（10%NaOH） ∶ w（檸檬醛）=4%，反應溫度60℃，反應時(shí)間3 h。合成紫羅蘭酮優(yōu)化工藝條件：物料比n（檸檬醛） ∶ n（H3PO4）=1 ∶ 1，反應溫度40℃，反應時(shí)間3 h。 |
| 關(guān)鍵詞：檸檬醛；紫羅蘭酮；正交法 |
| 中圖分類(lèi)號：TQ655 文獻標識碼：A 文章編號：1009-9212（2017）04-0036-03 |
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| Synthesis of Ionone from Citral Using Orthogonal Method |
| YANG Hai-kuan, WEN SHI-fang, LI Jiang, ZHANG Ting, WANG XIN-dong
(Camphor Engineering and Technology Research Center for State Forestry Administration, Jiangxi Academy of Forestry, Nanchang 330032, China) |
| Abstract：The pseudoionone was synthesized from citral and acetone by aldol condensation using sodium hydroxide as catalyst. The ionone was synthesized by cyclization using phosphoric acid as catalyst. The optimized synthesis technology of ionone from citral by one step were studied using orthogonal method. The optimized synthesis technology of pseudoionone were as following: mole ratio of citral to acetone was of 1:6, mass ratio of 10% sodium hydroxide to citral was of 4%, reaction temperature was of 60℃, reaction time was of 3 h. The optimized synthesis technology of ionone were, mole ratio of citral to phosphoric acid was of 1∶6, reaction temperature was of 40℃, reaction time was of 3 h. |
| Key words：citral; ionone; orthogonal test |
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基金項目：江西省重大科技專(zhuān)項“樟屬珍稀香料植物優(yōu)良系選育及利用研究”（20143ACF60014）。
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作者簡(jiǎn)介：楊海寬（1985-），男，江西吉安人，助理研究員，碩士，研究方向：林產(chǎn)化學(xué)加工工程（E-mail：Yanghaikuan1985@163.com）
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收稿日期：2017-08-13
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