| 第 32 卷第 4 期 |  | Vol. 32 No. 4 | | 2002 年 8 月 | Aug 2002 |
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所屬欄目：其它
1-溴-5-氯戊烷的合成方法研究 |
| 呂志果; 李英春; 郭振美; 周昕(青島科技大學(xué)化工與制藥學(xué)院; 山東青島; 266042) |
| 摘 要：報道了采用無(wú)水氯化鋅和硫酸復合催化劑 ,正庚烷作為鹵代反應的分水劑 ,將 1,5 戊二醇同時(shí)用氯化氫和溴化氫鹵化反應一步制取 1 溴 5 氯戊烷的實(shí)驗結果。實(shí)驗考察了反應溫度、催化劑用量、原料氣配比、鹵化反應時(shí)間等因素對產(chǎn)物收率的影響。實(shí)驗確定 :在反應溫度為 95℃左右 ,采用濃硫酸 (0 5 % )和無(wú)水氯化鋅 (2 0 % )復合催化劑 ,用HCl∶HBr(mol)為 3 0～ 3 5的原料氣將 1,5 戊二醇鹵化 ,反應 14h后產(chǎn)物中 1 溴 5 氯戊烷的含量達到 80 %以上。 |
| 關(guān)鍵詞：鹵化反應; 1; 5-戊二醇; 1-溴-5-氯戊烷; 協(xié)同催化 |
| 中圖分類(lèi)號：TQ222 文獻標識碼：A 文章編號：1009-9212(2002)04-0026-02 |
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| Study On The Preparation of 1-Bromo-5-chloro-Pentane |
| L Zhi-guo; et al.（Chemical and Pharmacy Institute of Qingdao University of Science & Technology; 266042; China） |
| Abstract：Bromo 5 chloro Pentane was prepared by halogenation of 1,4 pentanediol in one step,in which multiple catalyst of vitriol and anhydrous zinc chloride was used,and n heptane was used as entrainment of water.The optimized condition of halogenation as follows:the reaction temperature was 95℃,dosage of catalyst were 0.5%wt H 2SO 4,2.0%wt ZnCl 2,the mole ratio of HCl and HBr were 3.0～3.5, and halogenation time was 14 hours. The content of 1 Bromo 5 chloro Pentane was more than 80%wt under the optimize... |
| Key words：Bromo 5 chloro Pentane; 1; 5 pentanediol |
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收稿日期：2002-05-13
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