| 第 48 卷第 5 期 |  | Vol. 48 No. 5 | | 2018 年 10 月 | Oct 2018 |
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所屬欄目：專(zhuān)論與綜述
以吡唑萘菌胺為例探究農藥的開(kāi)發(fā)和優(yōu)化策略 |
| 趙 琳，代光輝*
(上海交通大學(xué) 農業(yè)與生物學(xué)院 植物健康與天然產(chǎn)物實(shí)驗室，農業(yè)部都市農業(yè)（南方）開(kāi)放重點(diǎn)實(shí)驗室，上海 200240） |
| 摘 要：以吡唑萘菌胺為例,介紹琥珀酸脫氫酶抑制劑（SDHIs）殺菌劑的作用機理和發(fā)展脈絡(luò )，結合SDHIs殺菌劑的抗性和產(chǎn)品生命周期問(wèn)題簡(jiǎn)要分析了產(chǎn)品開(kāi)發(fā)的一些考慮因素，以及產(chǎn)品的市場(chǎng)防御策略，為農藥新品種的開(kāi)發(fā)提供啟示。 |
| 關(guān)鍵詞：SDHIs殺菌劑；產(chǎn)品優(yōu)化；鹵素替代；作物抗性；劑型選擇；生命周期 |
| 中圖分類(lèi)號：S482.2 文獻標識碼：B 文章編號：1009-9212（2018）05-0009-05 |
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| Pesticides Development and Optimization Strategy with Isopyrazam as A Case |
| ZHAO Lin，DAI Guang-hui*
(Plant Health and Natural Products Lab, Key Lab of Urban Agriculture (South), Ministry of Agriculture, School of Agriculture and Biology, Shanghai Jiao Tong University, Shanghai 200240, China) |
| Abstract：With isopyrazam as a case, this paper focuses on Succinate Dehydrogenase Inhibitors (SDHIs) Fungicides, introducing the mode of actions (MOA) and market development history. It integrates the crop resistance and product life cycle issue of SDHIs fungicides to investigate and analyze the factors for new products development and market defense behaviors. The paper tries to use SDHIs fungicide as an example to develop the general framework and summarize the basic optimization strategy of pesticides, thus to provide clues for researchers. |
| Key words：SDHIs fungicides; halogen substitution; molecule optimization; crop resistance; formulation type selection; life cycle |
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作者簡(jiǎn)介：趙 琳 (1981-), 男，山東平度人，碩士，研究方向：植物保護。
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聯(lián) 系 人：代光輝，教授，博士生導師，研究方向：植物病理學(xué)和植物源農藥研究（E-mail: ghdai@sjtu.edu.cn）
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收稿日期：2018-06-29
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