| 第 49 卷第 6 期 |  | Vol. 49 No. 6 | | 2019 年 12 月 | Dec 2019 |
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所屬欄目：功能材料
高品質(zhì)戊基三聯(lián)苯腈的制備及提純 |
| 岳 剛，井 昭*，王利民，禹 凱，關(guān)登仕
（河北美星化工有限公司，河北 辛集 052360） |
| 摘 要：以4′-正戊基聯(lián)苯硼酸和對氯苯腈為原料，經(jīng)過(guò)Suzuki偶聯(lián)制備了戊基三聯(lián)苯腈。研究了堿和溶劑對反應轉化率的影響，以及重結晶溶劑的選擇。優(yōu)化的反應條件為：堿為無(wú)水碳酸鉀，反應溶劑為甲苯和N，N-二甲基甲酰胺，溫度85~90℃，4 h轉化率為96.3%，經(jīng)二甲苯和乙醇（v∶v=10∶1）提純后純度大于99.9%（GC），收率高達70%。 |
| 關(guān)鍵詞：Suzuki偶聯(lián)；戊基三聯(lián)苯腈；液晶中間體 |
| 中圖分類(lèi)號：TQ24 文獻標識碼：A 文章編號：1009-9212（2019）06-0064-03 |
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| Preparation and Purification of High-purity Pentyl Terphenyl Nitrile |
| YUE Gang, JING Zhao*, WANG Li－min, YU Kai, GUAN Deng－shi
(Hebei Maison Chemical CO., Ltd., Xinji 052360, China) |
| Abstract：The pentyl terphenyl nitrile was prepared by Suzuki coupling 4'-pentyl-4-biphenylboronic acid with p-chlorobenzonitrile. The effects of different bases and solvents on the conversion rate of the reaction and the choice of purification solvent were investigated. The optimum conditions for the reaction were determined: the base was potassium carbonate; the solvents were toluene and N,N-dimethylformamide; the conversion rate was 96.3% at 85~90℃ after 4 h; the purity after purification by xylene and ethanol (v∶v=10∶1) was more than 99.9%(GC) with the yield as high as 70% |
| Key words：Suzuki coupling; pentyl terphenyl nitrile; liquid crystal intermediate |
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作者簡(jiǎn)介：岳 剛（1973-），男，河北唐山人，主要從事液晶等顯示材料方面的研究（E-mail：maisonyue@126.com）。
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聯(lián) 系 人：井 昭，碩士，主要從事液晶單體及中間體的研究（E-mail：maisonjingzhao@126.com）。
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收稿日期：2019-12-03
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