| 第 33 卷第 3 期 |  | Vol. 33 No. 3 | | 2003 年 6 月 | Jun 2003 |
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所屬欄目：其它
微波輻射活性炭固載對甲苯磺酸催化合成氯乙酸異丙酯 |
| 施磊; 吳東珩; 蘇廣均; 吳東輝(南通工學(xué)院化工系; 南通第三制藥廠(chǎng); 江蘇南通; 226007; 226300) |
| 摘 要：報道了用活性炭固載對甲苯磺酸作催化劑 ,微波輻射法合成氯乙酸異丙酯。當微波輻射功率為 160W ,催化劑用量為 2.0g時(shí) ,反應 45min ,氯乙酸異丙酯的收率為 78.3% ,純度為 99.8%。同時(shí)發(fā)現在微波輻射下 ,酯化反應速率、收率均明顯高于常規加熱方式。 |
| 關(guān)鍵詞：微波輻射; 氯乙酸異丙酯; 活性炭; 對甲苯磺酸 |
| 中圖分類(lèi)號：O643.32 文獻標識碼：A 文章編號：1009-9212(2003)03-0037-02 |
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| Synthesis of Isopropyl Chloroacetate Catalyzed by PTSA Supported on Activated Carbon Under Microwave irradiation |
| SHI Lei 1; WU Dong heng 2 etc.（1.Departmet of Chemical Engineering; Nantong Institute of Technology; nantong 226007; China; 2. Nantong Third Pharmaceutical Factory; Nantong 226300; China） |
| Abstract：It was reported that the synthesis of isopropyl chloroacetate catalyzed by p toluenesulfonic acid(PTSA) supported on activated carbon under microwave irradiation. When the power of microwave irradiation is 160?w, amount of catalyst is 2.0?g, reaction time is 45?min, yield and purity of the product are 78.3% and 99.8% respectively. In addition, it was found that under microwave irradiation, the reaction rate of esterification, and yield of the product is higher than that of conventional heating method. |
| Key words：microwave irradiation; isopropyl chloroacetate; active carbon; P toluenesulfonic acid |
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收稿日期：2002-11-12
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