| 第 33 卷第 3 期 |  | Vol. 33 No. 3 | | 2003 年 6 月 | Jun 2003 |
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所屬欄目：專(zhuān)論與綜述
7-氨基去乙酰氧基頭孢烷酸生產(chǎn)工藝研究進(jìn)展 |
| 劉越; 王靜康(天津大學(xué)化工學(xué)院; 300072) |
| 摘 要：介紹了 7 氨基去乙酰氧基頭孢烷酸化學(xué)法合成工藝 ,綜述了酶法和發(fā)酵法合成7-ADCA的研究現狀。生物法合成經(jīng)濟且環(huán)境友好 ,是工業(yè)中合成 7-ADCA的發(fā)展方向 |
| 關(guān)鍵詞：7-ADCA; 化學(xué)法; 生物法; 酶法; 發(fā)酵法 |
| 中圖分類(lèi)號：R978.1 文獻標識碼：A 文章編號：1009-9212(2003)03-0001-03 |
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| Progress in the Production Technology of 7-amino Desacetoxy Cephalosporanic Acid |
| LIU Yue etc.（Institute of Chemical Engineering of Tianjin University; Tianjin; 300072; China） |
| Abstract：amino desacetoxycephalosporanic acid(7 ADCA) is a key intermediate for the preparation of synthetic commercial cephalosporins. up to date, the methods favored in industry to prepare 7 ADCA involved complex chemical steps. These complex chemical processes are both expensive and noxious to the environment. With the increasing knowledge of strain improvement techniques, the production level of antibiotics increased dramatically in the past years. As a result, a lot of inventions related to the bioprocess of ... |
| Key words：ADCA; chemical means; bioprocess |
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收稿日期：2002-12-18
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