| 第 33 卷第 4 期 |  | Vol. 33 No. 4 | | 2003 年 8 月 | Aug 2003 |
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所屬欄目：其它
由對二氯苯合成3,4-二氟氯苯的研究 |
| 張翠娥; 陳興泉; 王敏文; 劉鴻(西安近代化學(xué)研究所; 陜西西安) |
| 摘 要：報道了由對二氯苯一步直接氟化制備3,4-二氟氯苯的方法。將對二氯苯用硝硫混酸硝化獲得2,5-二氯硝基苯,并以氟化鉀為氟化劑,在四苯基溴化膦催化下于環(huán)丁砜等高沸點(diǎn)溶劑中直接進(jìn)行氟化,經(jīng)水蒸氣蒸餾和分餾提純獲得產(chǎn)品。硝化收率95%以上,氟化精餾收率49.8%,產(chǎn)品純度98%以上。 |
| 關(guān)鍵詞：對二氯苯; 2; 5-二氯硝基苯; 3; 4-二氟氯苯; 制備 |
| 中圖分類(lèi)號：TQ226.37 文獻標識碼：A 文章編號：1009-9212(2003)04-0022-02 |
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| The Synthesis of 3, 4-Difluorochlorobenzene from p-Dichlorobenzene |
| ZHANG Cui e; etc（Xi'an Modern Chemistry Research Institute; Xi'an 710065; China） |
| Abstract：The synthesis method of 3, 4-difluorochlorobenzene was reported by one step direct fluoration of p-dichlorobenzene 2, 5 dichloronitrobenzene was synthesized by nitrating p-dichlorobenzene with nitric acid and sulfuric acid. In the process of direct fluoration, tetraphenyl phosphonium bromide, potassium fluoride and sulfolane was used as catalyst, fluorating agent, and high boiling point agent respectively. The terminal product was gotten by distillation in water vapor, fractionation, and purification. The... |
| Key words：p dichlorobenzene; 2; 5 dichloronitrobenzene; 3; 4 difluorochlorobenzene; preparation |
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收稿日期：2002-10-21
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