| 第 34 卷第 2 期 |  | Vol. 34 No. 2 | | 2004 年 4 月 | Apr 2004 |
|
所屬欄目：其它
3-芳胺甲烯基-6-甲基-6-胡椒基-5,6-二氫-2H-吡喃-2,4二酮的合成及殺菌活性 |
| 邱克明; 王有名; 何可(湖南省張家界市環(huán)保局; 元素有機化學(xué)重點(diǎn)實(shí)驗室南開(kāi)大學(xué)元素有機化學(xué)研究所; 湖南張家界) |
| 摘 要：采用乙酰乙酸乙酯的雙負離子與胡椒基甲基酮反應,合成了5,6 二氫 6 甲基 6 胡椒基 2H 吡喃 2,4 二酮,然后與原甲酸三乙酯、芳胺進(jìn)行縮合反應,得到了3 芳胺甲烯基 5,6 二氫 6 甲基 6 胡椒基 2H 吡喃 2,4 二酮,其結構經(jīng)1HNMR和元素分析證實(shí)。生物活性初步測定表明,該類(lèi)化合物具有一定的殺菌活性。 |
| 關(guān)鍵詞：雙負離子; 胡椒基甲基酮; 殺菌 |
| 中圖分類(lèi)號：TQ455 文獻標識碼：A 文章編號：1009-9212(2004)02-0011-03 |
|
| Synthesis and Fungicidal Activity of 3-Anilinomethylene-5,6-dihydro-6-methyl-6-piperonyl-2H-pyran-2, 4-diones |
| QIU Ke-ming~1; WANG You-ming~2; HE Ke~2 （1; Bureau of Enviroment Protection; Zhangjiajie 427000 china; 2; State Key Laboratory of Elemental-Organic Chemistry; Institute of Elemental-Organic Chemistry; Nankai University; Tianjin; 300071; China） |
| Abstract：5, 6-Dihydro-6-methyl-6-piperonyl-2H-pyran-2, 4-dione, which was obtained by reacting dianion of acetoacetate with piperonyl methyl acetone, reacted with substituted anilines in the presence of ethyl orthoformate and 3-anilinomethylene-5, 6-dihydro-6-methyl-6-piperonyl-2H-pyran-2, 4-diones (2) were obtained.The Structures of compounds 2 were confirmed by 1~H NMR spectra and elemental analyses. Compound 2 was tested in vitro against many fungi such as P. Zeae, A. Solani, R. Solani, P. Piricola, C. Arachidica... |
| Key words：Dianion; Piperonyl methyl acetone; Fungicidal activity |
|
基金項目：國家自然科學(xué)基金青年基金資助(20302003)。
|
收稿日期：2004-02-17
|
| 閱讀全文 |
|