| 第 34 卷第 3 期 |  | Vol. 34 No. 3 | | 2004 年 6 月 | Jun 2004 |
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所屬欄目：其它
(S)-3-羥基丁內酯的合成 |
| 章小波; 蔣永祥; 汪勁松(浙江大學(xué)化學(xué)系; 杭州廣林生物醫藥有限公司; 浙江杭州) |
| 摘 要：以乳糖為原料經(jīng)分解酯化、官能團保護、酸化制得目標化合物。反應條件溫和,原料易得,方法簡(jiǎn)單,具有一定的工業(yè)化應用前景。 |
| 關(guān)鍵詞：（S）3羥基丁內酯; 蘋(píng)果酸; 酯化; 合成 |
| 中圖分類(lèi)號：TQ225.24 文獻標識碼：A 文章編號：1009-9212(2004)03-0025-02 |
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| Synthesis of (S)-3-Hydroxybutyrolactone |
| ZHANG Xiao-bo; JIANG Yong-xiang; WANG Jin-song （1. Department of Chemistry; Zhe jiang University; Hangzhou 310027; China; 2. Hangzhou Great Forest Biomedical Co.Ltd.; Hangzhou 310028; China） |
| Abstract：Use lactose as the raw material, the (s)-3-hydroxybutyrolactone was obtained through reaction steps of decomposition, esterification, protection of function group, acidification. Not only the raw material was easily obtained but the condition was more moderate and the synthesis way was simple, which make it more suitable for industrial process. |
| Key words：（S）-3-Hydroxybutyrolactone; Malic Acid; Esterification; Synthesis |
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收稿日期：2003-12-12
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