| 第 34 卷第 4 期 |  | Vol. 34 No. 4 | | 2004 年 8 月 | Aug 2004 |
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所屬欄目：其它
相轉移催化氧化合成氯代苯甲酸 |
| 吳美芝; 曾明; 熊立武; 李曉如(湖南科技職業(yè)學(xué)院; 湖南長(cháng)沙) |
| 摘 要：研究了以季銨鹽A 1為催化劑,KMnO4作氧化劑,催化氧化鄰、對位氯代甲苯合成鄰、對位氯代苯甲酸,考察了不同的相轉移催化劑的催化活性、催化劑的用量、反應溫度、反應時(shí)間、KMnO4用量、水的用量等對反應的影響。優(yōu)化反應條件:反應物料比為,氯代甲苯∶KMnO4為∶A 1∶H2O≈1∶2.6∶0.05∶300(mol),反應溫度為93℃,反應時(shí)間為2.5h,在中性條件下進(jìn)行反應,鄰、對位氯代苯甲酸的收率分別可達76.4%、76.9%。實(shí)驗結果表明,季銨鹽A 1對此反應是一種優(yōu)良的相轉移催化劑。 |
| 關(guān)鍵詞：相轉移催化氧化; 季銨鹽A1; 高錳酸鉀; 氯代甲苯; 氯代苯甲酸 |
| 中圖分類(lèi)號：TQ245.3 文獻標識碼：A 文章編號：1009-9212(2004)04-0042-03 |
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| Phase Transfer Catalytic Synthesis of Chlorobenzoic Acid With Quaternary Ammonium Salt A-1 |
| WU Mei-zhi; ZENG Ming; XIONG Li-wu; LI Xiao-ru （Hunan Vocational College of Science & Technology; Changsha 410118; China） |
| Abstract：The catalytic synthesis of o-,p-chlorobenzoic aicd with phase transfer catalyst(PTC), quaternaty ammonium salt A-1,was reported. The effects of different factors,such as PTC activity and amount,reaction temperature and time, the amount of KMnO4 and H_2O, on the yield of chlorobezoic acid were investigated. The optimal reaction conditions were that the mole ratio of chlorotoluene to KMnO_4 to A-1 to H_2O was about 1∶2.6:∶.05∶300,the reaction temperature and time were 93?℃ and 2.5?h respectively and the react... |
| Key words：phase trasfer catalytic oxidation; quaternary ammonium salt-1; o-; p-chloroluene; p-chlorobenzoic acid; potassium permanganate |
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收稿日期：2004-06-14
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