| 第 35 卷第 2 期 |  | Vol. 35 No. 2 | | 2005 年 4 月 | Apr 2005 |
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所屬欄目：其它
偕二溴環(huán)丁烷的合成 |
| 羅耀華; 林丹; 蔣玉仁; 劉佳佳(湖南大學(xué)衡陽(yáng)分�；は�; 中南大學(xué)化學(xué)化工學(xué)院; 湖南衡陽(yáng); 湖南長(cháng)沙) |
| 摘 要：以CH2(COOEt)2為原料,經(jīng)烷基化、還原、磺�；�、環(huán)化、水解和脫羧溴置換六步反應,合成了烴基為苯基、正丁基和乙基的三種1,1二溴3烴基環(huán)丁烷化合物。結果表明合成操作簡(jiǎn)便,條件易控制、提出的合成路線(xiàn)可行。 |
| 關(guān)鍵詞：1; 1-二溴-3-烴基環(huán)丁烷; 丙二酸二乙酯; 合成 |
| 中圖分類(lèi)號：TQ231.1 文獻標識碼：A 文章編號：1009-9212(2005)02-0032-03 |
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| Synthesis of 1,1-Dibromocyclobutanes |
| LUO Yao- hua;LIN-Dan;JIANG Yu-ren;LIU Jia-jia(1.Department of Chemistry;Hengyang College of Hunan university;Hengyang 421001; China;2.College of Chemistry and Chemical Engineering; Central South University; Changsha 410083;China) |
| Abstract：The synthesis of cyclobutane derivatives including 1,1-dibromo-3-phenylcyclobutane, 1,1-dibromo-3-ethylcyclobutane and 1,1-dibromo-3-ethylcyclobutane was studied in this paper. The synthesis routes involves such reactions as alkylation of diethyl malonate, reduction of ester, sulfonylation of alcohol, cyclization of sulfonylate and diethyl malonate, hydrolysis of ester and substitution of carboxyl group with bromine. The results show that the suggested synthesis method is simple, convenient and feasible to ... |
| Key words：1; 1-dibromo-3-alkylcyclobutanes; diethyl malonate; synthesis |
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收稿日期：2004-12-12
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