| 第 35 卷第 6 期 |  | Vol. 35 No. 6 | | 2005 年 12 月 | Dec 2005 |
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所屬欄目：醫藥及中間體
HPLC法測定-α乙酰氨基-α-乙酯基-β-(3-吲哚)-丙酸乙酯 |
| 丁玲玲; 王守凱; 趙海(中鋼集團鞍山熱能研究院; 遼寧鞍山) |
| 摘 要：采用Hypersill BDS C18色譜柱,以甲醇-水(60:40)為流動(dòng)相,流速1.0 mL.min-1,233nm為檢測波長(cháng),建立測定α-乙酰氨基-α-乙酯基-β-(3-吲哚)-丙酸乙酯的高效液相色譜法。進(jìn)樣量在4～20μg范圍內線(xiàn)性關(guān)系良好(r=0.9999)。RSD不大于0.68%。方法操作簡(jiǎn)單,分析速度快、準確,適用于α-乙酰氨基-α-乙酯基-β-(3-吲哚)-丙酸乙酯的質(zhì)量控制分析。 |
| 關(guān)鍵詞：α-乙酰氨基-α-乙酯基-β-（3-吲哚）-丙酸乙酯; HPLC; 分析 |
| 中圖分類(lèi)號：TQ225.24+1 文獻標識碼：A 文章編號：1009-9212(2005)06-0037-02 |
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| Determination of α-Acotamino-α-Carbethoxy-β-(3-indole)-propionate by HPLC |
| DING Ling-ling; WANG Shou-kai （China Steel Group Anshan Research Institute Of Thermo-Energy; Anshan 114004; China） |
| Abstract：A HPLC method was established for the determination of α-acetamino-α-carbethoxy-β-(3-indole)-propionate.The HPLC system consisted of Hypersill BDS C18 column(4.6 mm×200 mm,5um),methanol-water(60:40 v/v) mixture as mobile phase,detection wavelength 233nm,flow rate 1.0 ml.min-1 and column temperature at room temperature.The linear range is 4～20 μg(r=0.9999),and RSD less than 0.68%,indicating that the method was simple,quick,accurate,and suitable for the quality control of the product α-acetamino-α-carbethoxy-... |
| Key words：HPLC; α-acetamino-α-carbethoxy-β-（3-indole）-propionate.; analysis |
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收稿日期：2005-09-08
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