| 第 36 卷第 1 期 |  | Vol. 36 No. 1 | | 2006 年 2 月 | Feb 2006 |
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所屬欄目：醫藥及中間體
1,2,3-三氟-4-硝基苯合成方法改進(jìn) |
| 張海濱(南通江山農藥化工股份有限公司; 江蘇南通) |
| 摘 要：介紹了一種合成1,2,3-三氟-4-硝基苯的新方法:隨著(zhù)近年來(lái)三氯苯生產(chǎn)技術(shù)的發(fā)展,以1,2,3-三氯苯為起始原料,經(jīng)硝化、氟化兩步反應制得1,2,3-三氟-4-硝基苯,產(chǎn)品含量大于99%,收率60%,具有反應步驟少、操作簡(jiǎn)單等優(yōu)點(diǎn)。 |
| 關(guān)鍵詞：1; 2; 3-三氟-4-硝基苯; 3-三氯苯; 中間體; 合成 |
| 中圖分類(lèi)號：TQ246.1 文獻標識碼：A 文章編號：1009-9212(2006)01-0045-02 |
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| The new Method for the Synthesis of 1,2,3-trifluoro-4-nitrobenzene |
| ZHANG Hai-bin（Nantong Jiangshan Agrochemical & chemicals Co.; Ltd; Nantong 226006; China） |
| Abstract：With the improvement of producing 1,2,3-trichlorobenzene,a new method was given for synthesis of 1,2,3-trifluoro-4-nitrobenzene:1,2,3-trichlorobenzene was produced 1,2,3-trifluoro-4-nitrobenzene via nitration and fluorination,the purity of product was over 99%,and the yield 60%.The method had the advantages such as the simple reaction steps and easy operation. |
| Key words：1; 2; 3-Trifluoro-4-nitrobenzene; 3-Trichlorobenzene; Intermediate; Synthesis |
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收稿日期：2005-09-05
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