| 第 36 卷第 4 期 |  | Vol. 36 No. 4 | | 2006 年 8 月 | Aug 2006 |
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所屬欄目：香精香料
相轉移催化合成大茴香腈的研究 |
| 黃祖良; 梁威麗; 覃維雪; 陸蘭芬; 黎昊靈(右江民族醫學(xué)院化學(xué)教研室; 廣西百色) |
| 摘 要：以5mL(0.04mol)大茴香醛為原料,在95%乙醇中制備大茴香醛肟,進(jìn)一步在相轉移催化劑作用下以甲苯作帶水劑使大茴香醛肟脫水生成大茴香腈。優(yōu)化反應條件為:相轉移催化劑類(lèi)型為十六烷基三甲基溴化銨(HDTMA),其與大茴香醛的用量比(m/m)為0.02,NaOH與大茴香醛的用量比(m/m)以0.08為宜,反應時(shí)間為1.5h。在此條件下,從大茴香醛肟到大茴香腈的最高收率達90.7%,并用IR表征了產(chǎn)物的結構。 |
| 關(guān)鍵詞：大茴香醛; 大茴香醛肟; 大茴香腈; 合成; 堿相轉移催化劑 |
| 中圖分類(lèi)號：TQ226.61 文獻標識碼：A 文章編號：1009-9212(2006)04-0035-02 |
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| Synthesis of Anisonitrile by Base Phase Transfer Catalysis |
| HUANG Zu-liang; LIANG Wei-li; QIN Wei-xue; LU Lan-fen; LI Hao-ling （Department of Chemistry; Youjiang Medical College for Nationalities; Baise 533000; China） |
| Abstract：Synthesis of anisonitrile was carried out from anisaldehyde in the laboratory. Anisaldehyde was tranfered into aldoxime in the presence of 95% ethanol,and then gave anisonitrile using toluene as dehydrant. The optimal reaction conditions were as follow:0.1 g base phase transfer catalsis cetyltrimethyl ammonium bromide,0.4~0.5g NaOH and 1.5 h of reaction time. Under these conditions,the highest yield of anisonitrile from aldoxime was up to 90.7%,and the product anisonitrile was characterized by IR. |
| Key words：anisaldehyde; aldoxime; anisonitrile; synthesis; phase transfer bationase-catalsis |
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收稿日期：2006-05-08
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