| 第 36 卷第 5 期 |  | Vol. 36 No. 5 | | 2006 年 10 月 | Oct 2006 |
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所屬欄目：農藥及中間體
5-降冰片烯-2-醛的合成研究 |
| 王彥麗; 高中良; 趙連營(yíng); 劉雁(河北工業(yè)大學(xué)化工學(xué)院) |
| 摘 要：2-氯-5-氯甲基吡啶是生產(chǎn)吡蟲(chóng)啉、吡蟲(chóng)清和噻蟲(chóng)啉等的重要中間體,5-降冰片烯-2-醛是環(huán)戊二烯-丙稀醛法合成2-氯-5-氯甲基吡啶第一步反應中得到的中間產(chǎn)物。5-降冰片烯-2-醛由環(huán)戊二烯和丙稀醛發(fā)生狄爾斯-阿爾德(Diels-Alder)反應而成。以正交實(shí)驗方式優(yōu)化出5-降冰片烯-2-醛的反應條件�？疾榱嗽吓浔�、反應溫度和反應時(shí)間對反應的影響,并對不同的保溫溫度進(jìn)行考查,確定出最佳的保溫溫度。 |
| 關(guān)鍵詞：除草劑; 三氟啶磺隆; 2-巰基-3-芐氧基吡啶; 2-氯-3-羥基吡啶 |
| 中圖分類(lèi)號：TQ224.15 文獻標識碼：A 文章編號：1009-9212(2006)05-0054-03 |
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| Synthesis of 5-Norbornene-2-carboxaldehyde |
| WANG Yan-li; GAO Zhong-liang; ZHAO Lian-ying; LIU Yan（College of Chemical Enginering; Hebei University of Technology; Tianjin 300130; China） |
| Abstract：2-Chloro-5-chloromethylpyridine was known as an important intermediate of insecticide such as imidacloprid,acetamiprid and thiacloprid.5-Norbornene-2-carboxaldehyde was the first intermediate of 2-chloro-5-chloromethylpyridine synthesized through dicyclopentadiene-acrylic aldehyde method.5-Norbornene-2-carboxaldehyde was prepared by acrylic aldehyde and dicyclopentadiene,the optimum reaction conditions were obtained via orthogonal experiments.The effect of the proportion of raw materials,the reaction temper... |
| Key words：dicyclopentadiene; acrylicaldehyde; 5-norbornene-2-carboxaldehyde |
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收稿日期：2006-07-10
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